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Carcinogenesis In a very life time carcinogenicity analyze carried out in B6C3F1 mice, methylphenidate caused an increase in hepatocellular adenomas, and in males only, an increase in hepatoblastomas at a every day dose of around 60 mg/kg/day. This dose is approximately two periods the MRHD of 60 mg/day supplied to children on mg/m2 foundation.Phys

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